Nanocs, Inc. - A Global Supplier in Life Science and Nanotechnology
Nanocs, Inc. is a US-based global material supplier founded in 2001 by a group of scientists with strong academic backgrounds in chemistry, biology, and nanotechnology. The company has evolved into a leading enterprise in life science research, serving clients across several key sectors: pharmaceutical companies for drug development, formulation, and pre-clinical trials; university, industry, and government research laboratories; and biomedical device and diagnostic companies. With its central R&D and production facilities in Boston, Nanocs has also established offices in New York, Shanghai, and Singapore, and supplies customers in over 50 countries.
Continue…Core Business and Focus
The company???s core business centers on the design, synthesis, and supply of innovative life science products and services for biomedical research and technological development. Nanocs leverages expertise in material science, bioconjugation, and polymer chemistry to offer high-quality reagents and customized services that facilitate drug delivery, medical device fabrication, and diagnostics.
Products and Product Lines
Nanocs offers an extensive catalog of products, which are typically organized into several major categories:
PEG Derivatives and Reagents
Polyethylene glycol (PEG) and its derivatives are a flagship product line, essential for PEGylation, crosslinking, and labeling in bioconjugation and drug formulation. The offerings include a diverse range of functionalized PEGs:
* Amine Reactive PEGs: Such as Succinimidyl PEG NHS (mPEG-NHS(SC)).
* Thiol Reactive PEGs: Including Maleimide PEG (mPEG-MAL).
* Heterobifunctional PEGs: Such as Maleimide PEG NHS (MAL-PEG-NHS).
* Biotinylated PEGs: For instance, Biotin-PEG-NHS (NHS PEG Biotin).
* Lipid PEG Derivatives: Like DSPE PEG Maleimide (DSPE-PEG-MAL) and mPEG-DSPE, which are crucial for forming Lipid Nanoparticles (LNP).
* Fluorescent PEGs, Click PEG Derivatives, Polymerizable PEGs, and Multiarm PEGs.
Nanoparticles and Beads
The company provides highly uniform and multifunctional nanoparticles that are central to drug delivery, imaging, and diagnostic applications:
* Gold Nanoparticles: Available in various sizes (e.g., 20 nm, 0.01% Au) and conjugations (e.g., Streptavidin Conjugated Gold Nanoparticles), as well as Gold Nanoshells and Gold Nanorods.
* Silica Particles & Beads: Such as FITC labeled Silica nanoparticles.
* Magnetic Nanoparticles & Beads: Including Super paramagnetic nanoparticles with iron oxide cores overcoated with biocompatible polymers, primarily for biomedical imaging, biospecies separation, and bioassay development.
* Other Nanomaterials: Silver Nanoparticles and Nanowires, Polystyrene Beads, Graphene Oxide, and Carbon Nanotubes (SWNTs and MWNTs).
Labels, Crosslinkers, and Biomolecules
Nanocs is a supplier of a rich array of reactive molecules for molecular labeling and bioconjugation.
* Fluorescent Dyes & Probes: Including Near IR fluorescent dyes for cellular and in-vivo imaging.
* Biomolecules: Functionalized biopolymers, labeled proteins, antibodies, enzymes, peptides, and nucleotides.
* Crosslinkers: Maleimide, NHS, hetero-functional, and homo-functional cross-linkers for connecting biomolecules.
Slides and Kits
The company also provides specialized substrates for material science and diagnostics:
* ITO Coated Glass Slides and Cover Slips.
* FTO Coated Glass Substrates.
* Surface Coated Functional Glass Slides.
* Nucleic Acid Purification Kits and kits for purification, conjugation, and labeling.
Services Offered
Nanocs provides high-value-added services leveraging its strong team in chemistry, biology, and material sciences. These services are critical for clients in drug delivery, medical device fabrication, and diagnostics.
* Bioconjugation and Labeling: Modification, labeling, and conjugation for nano/micro particles, proteins, enzymes, antibodies, peptides, and nucleotides. This includes fluorescence labeling, pegylation, and biotinylation.
* Chemical Synthesis: Custom molecule synthesis and modification for specific research needs.
* Particle Modification: Particle synthesis and modification, including custom conjugation for nanoparticles.
* Surface Modification: Surface modification, coating, and functionalization for medical devices, particles, and other substrates.
* Assay Development: Provision of services for bioassay development.
* Antibody Drug Conjugate (ADC) Development.
